Cargando…

A ROS-responsive polymeric prodrug nanosystem with self-amplified drug release for PSMA (−) prostate cancer specific therapy

BACKGROUND: The selectively accumulate in tumor site and completely release drug within cancer cells great limit the therapeutic effect of nano-drug delivery system. Moreover, absence of appropriate biomarker is one of the major challenges for prostate specific membrane antigen negative (PSMA (−)) p...

Descripción completa

Detalles Bibliográficos
Autores principales:	Wang, Yifan, Zhang, Yanqiu, Ru, Zhengxing, Song, Wei, Chen, Lin, Ma, Hao, Sun, Lizhu
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2019
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6709549/ https://www.ncbi.nlm.nih.gov/pubmed/31451114 http://dx.doi.org/10.1186/s12951-019-0521-z

Ejemplares similares

A pH/ROS Cascade‐Responsive Charge‐Reversal Nanosystem with Self‐Amplified Drug Release for Synergistic Oxidation‐Chemotherapy
por: Dai, Liangliang, et al.
Publicado: (2018)

Multiple stimuli-responsive nanosystem for potent, ROS-amplifying, chemo-sonodynamic antitumor therapy
por: Tang, JunJie, et al.
Publicado: (2021)

A co-delivery system based on chlorin e6-loaded ROS-sensitive polymeric prodrug with self-amplified drug release to enhance the efficacy of combination therapy for breast tumor cells
por: Wang, Cui, et al.
Publicado: (2023)

A prostate-specific membrane antigen (PSMA)-targeted prodrug with a favorable in vivo toxicity profile
por: Boinapally, Srikanth, et al.
Publicado: (2021)

Stimuli-Responsive Polymeric Nanosystem for Colon Specific Drug Delivery
por: Joseph, Sharon Kunnath, et al.
Publicado: (2020)

Engineering Polymeric Nanosystems against Oral Diseases
por: Mercadante, Valeria, et al.
Publicado: (2021)

Polymeric Nanoparticles with ROS‐Responsive Prodrug and Platinum Nanozyme for Enhanced Chemophotodynamic Therapy of Colon Cancer
por: Hao, Ying, et al.
Publicado: (2020)

pH and ROS sequentially responsive podophyllotoxin prodrug micelles with surface charge-switchable and self-amplification drug release for combating multidrug resistance cancer
por: Li, Chao, et al.
Publicado: (2021)

Tumor-specific activatable biopolymer nanoparticles stabilized by hydroxyethyl starch prodrug for self-amplified cooperative cancer therapy
por: Xiong, Yuxuan, et al.
Publicado: (2022)

A pH/ROS cascade-responsive and self-accelerating drug release nanosystem for the targeted treatment of multi-drug-resistant colon cancer
por: Chang, Na, et al.
Publicado: (2020)

Prostate-specific membrane antigen (PSMA)-targeted photodynamic therapy enhances the delivery of PSMA-targeted magnetic nanoparticles to PSMA-expressing prostate tumors
por: Ngen, Ethel J., et al.
Publicado: (2021)

Development and Evaluation of a PSMA-Targeted Nanosystem Co-Packaging Docetaxel and Androgen Receptor siRNA for Castration-Resistant Prostate Cancer Treatment
por: Zhang, Yingying, et al.
Publicado: (2022)

Cascade-amplifying synergistic effects of chemo-photodynamic therapy using ROS-responsive polymeric nanocarriers
por: Sun, Chun-Yang, et al.
Publicado: (2018)

PSMA Ligand Conjugated PCL-PEG Polymeric Micelles Targeted to Prostate Cancer Cells
por: Jin, Jian, et al.
Publicado: (2014)

Ultrasound Combined with Core Cross-Linked Nanosystem for Enhancing Penetration of Doxorubicin Prodrug/Beta-Lapachone into Tumors
por: Li, Qianyan, et al.
Publicado: (2020)

Dual-Drug Nanosystem: Etoposide Prodrug and Cisplatin Coloaded Nanostructured Lipid Carriers for Lung Cancer Therapy
por: Du, Min, et al.
Publicado: (2022)

Relaxation processes in hybrid organic-inorganic polymer nanosystems polymerized in situ
por: Iurzhenko, Maksym, et al.
Publicado: (2014)

Perspective highlights on biodegradable polymeric nanosystems for targeted therapy of solid tumors
por: Fathi, Marziyeh, et al.
Publicado: (2017)

Polymeric and lipid nanoparticles for delivery of self-amplifying RNA vaccines
por: Blakney, Anna K., et al.
Publicado: (2021)

The Self-Assembly and Design of Polyfunctional Nanosystems
por: Kashapov, Ruslan, et al.
Publicado: (2021)

Powering the plasma membrane Ca(2+)-ROS self-amplifying loop
por: Pottosin, Igor, et al.
Publicado: (2018)

Platinum-Induced Peripheral Neuropathy (PIPN): ROS-Related Mechanism, Therapeutic Agents, and Nanosystems
por: Hu, Xi, et al.
Publicado: (2021)

Key Modulation of ROS and HSP for Effective Therapy Against Hypoxic Tumor with Multifunctional Nanosystem
por: Ma, Bangzhen, et al.
Publicado: (2023)

Enzalutamide Enhances PSMA Expression of PSMA-Low Prostate Cancer
por: Staniszewska, Magdalena, et al.
Publicado: (2021)

Prostate-Specific Membrane Antigen (PSMA) Theranostics for Treatment of Oligometastatic Prostate Cancer
por: Plichta, Kristin A., et al.
Publicado: (2021)

Amplifying the efficacy of ALA-based prodrugs for photodynamic therapy using nanotechnology
por: Lou, Liang, et al.
Publicado: (2023)

Heterogeneity of prostate-specific membrane antigen (PSMA) and PSMA-ligand uptake detection combining autoradiography and postoperative pathology in primary prostate cancer
por: Wang, Hui, et al.
Publicado: (2023)

Expression of Prostate Specific Membrane Antigen (PSMA) in Breast Cancer
por: Unger, Clara, et al.
Publicado: (2022)

Progress in Diamanes and Diamanoids Nanosystems for Emerging Technologies
por: Tiwari, Santosh K., et al.
Publicado: (2022)

Photo-responsive polymeric micelles and prodrugs: synthesis and characterization
por: Wang, Shiu-Wei, et al.
Publicado: (2018)

Near-infrared light triggered multi-hit therapeutic nanosystem for tumor specific photothermal effect amplified signal pathway regulation and ferroptosis
por: Lian, He, et al.
Publicado: (2021)

A tumor cell membrane-coated self-amplified nanosystem as a nanovaccine to boost the therapeutic effect of anti-PD-L1 antibody
por: Li, Zhilin, et al.
Publicado: (2022)

Inhibitory prodrug mechanism for cysteine cathepsin-targeted self-controlled drug release
por: van Dalen, Floris J., et al.
Publicado: (2022)

Lectin-Targeted Prodrugs Activated by Pseudomonas aeruginosa for Self-Destructive Antibiotic Release
por: Meiers, Joscha, et al.
Publicado: (2022)

Focal therapy of prostate cancer: Assessment with prostate-specific membrane antigen (PSMA) imaging
por: Topoozian, Mark, et al.
Publicado: (2023)

Dual-Function Polymeric HPMA Prodrugs for the Delivery of miRNA
por: Peng, Zheng-Hong, et al.
Publicado: (2017)

The oncological characteristics of non‐prostate‐specific membrane antigen (PSMA)‐expressing primary prostate cancer on preoperative PSMA positron emission tomography/computed tomography
por: Veerman, Hans, et al.
Publicado: (2022)

Weibull Modeling of Controlled Drug Release from Ag-PMA Nanosystems
por: Corsaro, Carmelo, et al.
Publicado: (2021)

Catalysis of Transesterification Reactions by a Self-Assembled Nanosystem
por: Zaramella, Davide, et al.
Publicado: (2013)

Immunomodulatory Nanosystems
por: Feng, Xiangru, et al.
Publicado: (2019)

Cannot write session to /tmp/vufind_sessions/sess_o6qu8nnff5d2ube4g267ot2v6j