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Metabolic engineering of roseoflavin-overproducing microorganisms
BACKGROUND: Roseoflavin, a promising broad-spectrum antibiotic, is naturally produced by the bacteria Streptomyces davaonensis and Streptomyces cinnabarinus. The key enzymes responsible for roseoflavin biosynthesis and the corresponding genes were recently identified. In this study we aimed to enhan...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6709556/ https://www.ncbi.nlm.nih.gov/pubmed/31451111 http://dx.doi.org/10.1186/s12934-019-1181-2 |