Cargando…

Metabolic engineering of roseoflavin-overproducing microorganisms

BACKGROUND: Roseoflavin, a promising broad-spectrum antibiotic, is naturally produced by the bacteria Streptomyces davaonensis and Streptomyces cinnabarinus. The key enzymes responsible for roseoflavin biosynthesis and the corresponding genes were recently identified. In this study we aimed to enhan...

Descripción completa

Detalles Bibliográficos
Autores principales: Mora-Lugo, Rodrigo, Stegmüller, Julian, Mack, Matthias
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6709556/
https://www.ncbi.nlm.nih.gov/pubmed/31451111
http://dx.doi.org/10.1186/s12934-019-1181-2