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Bacterial load and inflammatory response in sputum of alpha-1 antitrypsin deficiency patients with COPD

BACKGROUND: Airway inflammation may drive the progression of chronic obstructive pulmonary disease (COPD) associated with alpha-1 antitrypsin deficiency (AATD), but the relationship between airway microbiota and inflammation has not been investigated. METHODS: We studied 21 non-treated AATD (AATD-no...

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Detalles Bibliográficos
Autores principales: Balbi, Bruno, Sangiorgi, Claudia, Gnemmi, Isabella, Ferrarotti, Ilaria, Vallese, Davide, Paracchini, Elena, Delle Donne, Lorena, Corda, Luciano, Baderna, Paolo, Corsico, Angelo, Carone, Mauro, Brun, Paola, Cappello, Francesco, Ricciardolo, Fabio LM, Ruggeri, Paolo, Mumby, Sharon, Adcock, Ian M, Caramori, Gaetano, Di Stefano, Antonino
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6709647/
https://www.ncbi.nlm.nih.gov/pubmed/31686800
http://dx.doi.org/10.2147/COPD.S207203