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Bacterial load and inflammatory response in sputum of alpha-1 antitrypsin deficiency patients with COPD
BACKGROUND: Airway inflammation may drive the progression of chronic obstructive pulmonary disease (COPD) associated with alpha-1 antitrypsin deficiency (AATD), but the relationship between airway microbiota and inflammation has not been investigated. METHODS: We studied 21 non-treated AATD (AATD-no...
Autores principales: | Balbi, Bruno, Sangiorgi, Claudia, Gnemmi, Isabella, Ferrarotti, Ilaria, Vallese, Davide, Paracchini, Elena, Delle Donne, Lorena, Corda, Luciano, Baderna, Paolo, Corsico, Angelo, Carone, Mauro, Brun, Paola, Cappello, Francesco, Ricciardolo, Fabio LM, Ruggeri, Paolo, Mumby, Sharon, Adcock, Ian M, Caramori, Gaetano, Di Stefano, Antonino |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Dove
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6709647/ https://www.ncbi.nlm.nih.gov/pubmed/31686800 http://dx.doi.org/10.2147/COPD.S207203 |
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