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Reconstructing B-cell receptor sequences from short-read single-cell RNA sequencing with BRAPeS

RNA sequencing of single B cells provides simultaneous measurements of the cell state and its antigen specificity as determined by the B-cell receptor (BCR). However, to uncover the latter, further reconstruction of the BCR sequence is needed. We present BRAPeS (“BCR Reconstruction Algorithm for Pai...

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Detalles Bibliográficos
Autores principales: Afik, Shaked, Raulet, Gabriel, Yosef, Nir
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Life Science Alliance LLC 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6709718/
https://www.ncbi.nlm.nih.gov/pubmed/31451449
http://dx.doi.org/10.26508/lsa.201900371