Modeling Retinitis Pigmentosa: Retinal Organoids Generated From the iPSCs of a Patient With the USH2A Mutation Show Early Developmental Abnormalities

Retinitis pigmentosa (RP) represents a group of inherited retinopathies with early-onset nyctalopia followed by progressive photoreceptor degeneration causing irreversible vision loss. Mutations in USH2A are the most common cause of non-syndromic RP. Here, we reprogrammed induced pluripotent stem ce...

Descripción completa

Detalles Bibliográficos
Autores principales: Guo, Yonglong, Wang, Peiyuan, Ma, Jacey Hongjie, Cui, Zekai, Yu, Quan, Liu, Shiwei, Xue, Yunxia, Zhu, Deliang, Cao, Jixing, Li, Zhijie, Tang, Shibo, Chen, Jiansu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6709881/
https://www.ncbi.nlm.nih.gov/pubmed/31481876
http://dx.doi.org/10.3389/fncel.2019.00361

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6709881/
https://www.ncbi.nlm.nih.gov/pubmed/31481876
http://dx.doi.org/10.3389/fncel.2019.00361

Ejemplares similares