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Modeling Retinitis Pigmentosa: Retinal Organoids Generated From the iPSCs of a Patient With the USH2A Mutation Show Early Developmental Abnormalities

Retinitis pigmentosa (RP) represents a group of inherited retinopathies with early-onset nyctalopia followed by progressive photoreceptor degeneration causing irreversible vision loss. Mutations in USH2A are the most common cause of non-syndromic RP. Here, we reprogrammed induced pluripotent stem ce...

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Detalles Bibliográficos
Autores principales:	Guo, Yonglong, Wang, Peiyuan, Ma, Jacey Hongjie, Cui, Zekai, Yu, Quan, Liu, Shiwei, Xue, Yunxia, Zhu, Deliang, Cao, Jixing, Li, Zhijie, Tang, Shibo, Chen, Jiansu
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2019
Materias:	Neuroscience
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6709881/ https://www.ncbi.nlm.nih.gov/pubmed/31481876 http://dx.doi.org/10.3389/fncel.2019.00361

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