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Cooperative adaptation to therapy (CAT) confers resistance in heterogeneous non-small cell lung cancer

Understanding intrinsic and acquired resistance is crucial to overcoming cancer chemotherapy failure. While it is well-established that intratumor, subclonal genetic and phenotypic heterogeneity significantly contribute to resistance, it is not fully understood how tumor sub-clones interact with eac...

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Detalles Bibliográficos
Autores principales: Craig, Morgan, Kaveh, Kamran, Woosley, Alec, Brown, Andrew S., Goldman, David, Eton, Elliot, Mehta, Ravindra M., Dhawan, Andrew, Arai, Kazuya, Rahman, M. Mamunur, Chen, Sidi, Nowak, Martin A., Goldman, Aaron
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6709889/
https://www.ncbi.nlm.nih.gov/pubmed/31449515
http://dx.doi.org/10.1371/journal.pcbi.1007278