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Cooperative adaptation to therapy (CAT) confers resistance in heterogeneous non-small cell lung cancer
Understanding intrinsic and acquired resistance is crucial to overcoming cancer chemotherapy failure. While it is well-established that intratumor, subclonal genetic and phenotypic heterogeneity significantly contribute to resistance, it is not fully understood how tumor sub-clones interact with eac...
| Autores principales: | , , , , , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6709889/ https://www.ncbi.nlm.nih.gov/pubmed/31449515 http://dx.doi.org/10.1371/journal.pcbi.1007278 |