Tbx1 and Foxi3 genetically interact in the pharyngeal pouch endoderm in a mouse model for 22q11.2 deletion syndrome

We investigated whether Tbx1, the gene for 22q11.2 deletion syndrome (22q11.2DS) and Foxi3, both required for segmentation of the pharyngeal apparatus (PA) to individual arches, genetically interact. We found that all Tbx1(+/-);Foxi3(+/-) double heterozygous mouse embryos had thymus and parathyroid...

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Detalles Bibliográficos
Autores principales: Hasten, Erica, Morrow, Bernice E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6709926/
https://www.ncbi.nlm.nih.gov/pubmed/31412026
http://dx.doi.org/10.1371/journal.pgen.1008301

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6709926/
https://www.ncbi.nlm.nih.gov/pubmed/31412026
http://dx.doi.org/10.1371/journal.pgen.1008301

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