Sodium cantharidate targets STAT3 and abrogates EGFR inhibitor resistance in osteosarcoma

Osteosarcoma is the most common primary malignant bone tumor in children and adolescents. Overactive EGFR signaling is frequently seen in osteosarcoma cells, and represents a potential therapeutic target. However, feedback activation of STAT3 after EGFR inhibition is linked to treatment resistance,...

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Detalles Bibliográficos
Autores principales: Ji, Xiang Lu, He, Ming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals 2019
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6710037/
https://www.ncbi.nlm.nih.gov/pubmed/31422383
http://dx.doi.org/10.18632/aging.102193

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6710037/
https://www.ncbi.nlm.nih.gov/pubmed/31422383
http://dx.doi.org/10.18632/aging.102193

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