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Downregulation of microRNA-218 is cardioprotective against cardiac fibrosis and cardiac function impairment in myocardial infarction by binding to MITF

Objective: This study is intended to figure out the function of microRNA-218 (miR-218) together with microphthalmia-associated transcription factor (MITF) on the cardiac fibrosis and cardiac function impairment in rat models of myocardial infarction (MI). Results: The rats with MI exhibited cardiac...

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Detalles Bibliográficos
Autores principales: Qian, Linfeng, Pan, Shaobo, Shi, Liping, Zhou, Yongyi, Sun, Lai, Wan, Zhedong, Ding, Yufang, Qian, Jia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6710048/
https://www.ncbi.nlm.nih.gov/pubmed/31408435
http://dx.doi.org/10.18632/aging.102112