Rejuvenation of brain, liver and muscle by simultaneous pharmacological modulation of two signaling determinants, that change in opposite directions with age

We hypothesize that altered intensities of a few morphogenic pathways account for most/all the phenotypes of aging. Investigating this has revealed a novel approach to rejuvenate multiple mammalian tissues by defined pharmacology. Specifically, we pursued the simultaneous youthful in vivo calibratio...

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Detalles Bibliográficos
Autores principales: Mehdipour, Melod, Etienne, Jessy, Chen, Chia-Chien, Gathwala, Ranveer, Rehman, Maryam, Kato, Cameron, Liu, Chao, Liu, Yutong, Zuo, Yi, Conboy, Michael J., Conboy, Irina M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals 2019
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6710051/
https://www.ncbi.nlm.nih.gov/pubmed/31422380
http://dx.doi.org/10.18632/aging.102148

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6710051/
https://www.ncbi.nlm.nih.gov/pubmed/31422380
http://dx.doi.org/10.18632/aging.102148

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