TGFβ1- miR-140-5p axis mediated up-regulation of Flap Endonuclease 1 promotes epithelial-mesenchymal transition in hepatocellular carcinoma

Flap Endonuclease 1 (FEN1) is a known oncogene in an array of cancers, but its role in hepatocellular carcinoma (HCC) remains obscure. In this study, we report that FEN1 expression was elevated in the Cancer Genome Atlas (TCGA) database which was verified in HCC tissue and hepatoma cell lines. Pears...

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Detalles Bibliográficos
Autores principales: Li, Chuanfei, Zhou, Di, Hong, Hao, Yang, Shuangyan, Zhang, Li, Li, Shiying, Hu, Peng, Ren, Hong, Mei, Zhechuan, Tang, Hui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals 2019
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6710057/
https://www.ncbi.nlm.nih.gov/pubmed/31402791
http://dx.doi.org/10.18632/aging.102140

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6710057/
https://www.ncbi.nlm.nih.gov/pubmed/31402791
http://dx.doi.org/10.18632/aging.102140

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