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MicroRNA-194 inactivates hepatic stellate cells and alleviates liver fibrosis by inhibiting AKT2

BACKGROUND: Activation of hepatic stellate cells (HSCs) is a pivotal event in the onset and progression of liver fibrosis. Loss of microRNA-194 (miR-194) has been reported in activated HSCs, but the actual role of miR-194 in liver fibrosis remains uncertain. AIM: To explore the role and potential me...

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Detalles Bibliográficos
Autores principales: Wu, Jun-Cheng, Chen, Rong, Luo, Xin, Li, Zheng-Hong, Luo, Sheng-Zheng, Xu, Ming-Yi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Baishideng Publishing Group Inc 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6710173/
https://www.ncbi.nlm.nih.gov/pubmed/31496625
http://dx.doi.org/10.3748/wjg.v25.i31.4468