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Mapping insoluble indole metabolites in the gastrointestinal environment of a murine colorectal cancer model using desorption/ionisation on porous silicon imaging

Indole derivatives are a structurally diverse group of compounds found in food, toxins, medicines, and produced by commensal microbiota. On contact with acidic stomach conditions, indoles undergo condensation to generate metabolites that vary in solubility, activity and toxicity as they move through...

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Detalles Bibliográficos
Autores principales: Rudd, David Andre, Benkendorff, Kirsten, Chahal, Charndeep, Guinan, Taryn, Gustafsson, Ove Johan Ragnar, Esmaeelian, Babak, Krysinska, Hanna, Pogson, Lisa, Voelcker, Nicolas Hans, Abbott, Catherine Anne
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6710270/
https://www.ncbi.nlm.nih.gov/pubmed/31451756
http://dx.doi.org/10.1038/s41598-019-48533-2