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Pheno-seq – linking visual features and gene expression in 3D cell culture systems

Patient-derived 3D cell culture systems are currently advancing cancer research since they potentiate the molecular analysis of tissue-like properties and drug response under well-defined conditions. However, our understanding of the relationship between the heterogeneity of morphological phenotypes...

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Detalles Bibliográficos
Autores principales: Tirier, Stephan M., Park, Jeongbin, Preußer, Friedrich, Amrhein, Lisa, Gu, Zuguang, Steiger, Simon, Mallm, Jan-Philipp, Krieger, Teresa, Waschow, Marcel, Eismann, Björn, Gut, Marta, Gut, Ivo G., Rippe, Karsten, Schlesner, Matthias, Theis, Fabian, Fuchs, Christiane, Ball, Claudia R., Glimm, Hanno, Eils, Roland, Conrad, Christian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6710272/
https://www.ncbi.nlm.nih.gov/pubmed/31451731
http://dx.doi.org/10.1038/s41598-019-48771-4