Development of Efficient AAV2/DJ-Based Viral Vectors to Selectively Downregulate the Expression of Neuronal or Astrocytic Target Proteins in the Rat Central Nervous System

Viral vectors have become very popular to overexpress or downregulate proteins of interest in different cell types. They conveniently allow the precise targeting of well-defined tissue areas, which is particularly useful in complex organs like the brain. In theory, each vector should have its own ce...

Descripción completa

Detalles Bibliográficos
Autores principales: Jollé, Charlotte, Déglon, Nicole, Pythoud, Catherine, Bouzier-Sore, Anne-Karine, Pellerin, Luc
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6710342/
https://www.ncbi.nlm.nih.gov/pubmed/31481874
http://dx.doi.org/10.3389/fnmol.2019.00201

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6710342/
https://www.ncbi.nlm.nih.gov/pubmed/31481874
http://dx.doi.org/10.3389/fnmol.2019.00201

Ejemplares similares