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Development of Efficient AAV2/DJ-Based Viral Vectors to Selectively Downregulate the Expression of Neuronal or Astrocytic Target Proteins in the Rat Central Nervous System
Viral vectors have become very popular to overexpress or downregulate proteins of interest in different cell types. They conveniently allow the precise targeting of well-defined tissue areas, which is particularly useful in complex organs like the brain. In theory, each vector should have its own ce...
Autores principales: | Jollé, Charlotte, Déglon, Nicole, Pythoud, Catherine, Bouzier-Sore, Anne-Karine, Pellerin, Luc |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6710342/ https://www.ncbi.nlm.nih.gov/pubmed/31481874 http://dx.doi.org/10.3389/fnmol.2019.00201 |
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