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Cryo-EM Reveals Architectural Diversity in Active Rotavirus Particles

Rotavirus is a well-studied RNA virus that causes severe gastroenteritis in children. During viral entry, the outer layer of the virion is shed, creating a double-layered particle (DLP) that is competent to perform viral transcription (i.e., mRNA synthesis) and launch infection. While inactive forms...

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Detalles Bibliográficos
Autores principales: Hauser, Mary, Dearnaley, William J., Varano, A. Cameron, Casasanta, Michael, McDonald, Sarah M., Kelly, Deborah F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Research Network of Computational and Structural Biotechnology 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6710475/
https://www.ncbi.nlm.nih.gov/pubmed/31467657
http://dx.doi.org/10.1016/j.csbj.2019.07.019