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Profile of tezacaftor/ivacaftor combination and its potential in the treatment of cystic fibrosis
Cystic fibrosis (CF) is a life-limiting autosomal recessive disease caused by dysfunction of the cystic fibrosis transmembrane conductance regulator (CFTR) ion channel. Management of CF has traditionally relied upon managing complications of CFTR protein dysfunction and this has led to a steady impr...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Dove
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6710479/ https://www.ncbi.nlm.nih.gov/pubmed/31692517 http://dx.doi.org/10.2147/TCRM.S165027 |