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Profile of tezacaftor/ivacaftor combination and its potential in the treatment of cystic fibrosis

Cystic fibrosis (CF) is a life-limiting autosomal recessive disease caused by dysfunction of the cystic fibrosis transmembrane conductance regulator (CFTR) ion channel. Management of CF has traditionally relied upon managing complications of CFTR protein dysfunction and this has led to a steady impr...

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Detalles Bibliográficos
Autores principales: Shiferaw, Dejene, Faruqi, Shoaib
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6710479/
https://www.ncbi.nlm.nih.gov/pubmed/31692517
http://dx.doi.org/10.2147/TCRM.S165027