Prooxidative Activity of Celastrol Induces Apoptosis, DNA Damage, and Cell Cycle Arrest in Drug-Resistant Human Colon Cancer Cells

Cancer resistance to chemotherapy is closely related to tumor heterogeneity, i.e., the existence of distinct subpopulations of cancer cells in a tumor mass. An important role is assigned to cancer stem cells (CSCs), a small subset of cancer cells with high tumorigenic potential and capacity of self-...

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Detalles Bibliográficos
Autores principales: Moreira, Helena, Szyjka, Anna, Paliszkiewicz, Kamila, Barg, Ewa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6710751/
https://www.ncbi.nlm.nih.gov/pubmed/31485297
http://dx.doi.org/10.1155/2019/6793957

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6710751/
https://www.ncbi.nlm.nih.gov/pubmed/31485297
http://dx.doi.org/10.1155/2019/6793957

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