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Hypoxia-Inducible Factors as an Alternative Source of Treatment Strategy for Cancer
Hypoxia-inducible factors (HIFs) are transcription factors that activate the transcription of genes necessary to circumvent to hypoxic (low oxygen level) environments. In carcinogenesis, HIFs play a critical role. Indeed, HIF-1α has been validated as a promising target for novel cancer therapeutics,...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Hindawi
2019
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6710762/ https://www.ncbi.nlm.nih.gov/pubmed/31485300 http://dx.doi.org/10.1155/2019/8547846 |