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A rapid and sensitive UPLC-MS/MS method for the determination of flibanserin in rat plasma: application to a pharmacokinetic study
BACKGROUND: In this work, we aim to develop and validate a fast, simple, and sensitive method for the quantitative determination of flibanserin and the exploration of its pharmacokinetics. METHODS: Ultra-performance liquid chromatography-tandem mass spectrometry (UHPLC-MS/MS) was the method of choic...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer International Publishing
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6710871/ https://www.ncbi.nlm.nih.gov/pubmed/31463480 http://dx.doi.org/10.1186/s13065-019-0620-9 |