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Modulating Ocular Scarring in Glaucoma Filtration Surgery Using the Epigenetic Adjunct Suberoylanilide Hydroxamic Acid

AIM: The aim of this study is to assess the effectiveness of suberoylanilide hydroxamic acid (SAHA), a histone deacetylase inhibitor (HDI) with a broad spectrum epigenetic activity, in improving filtration bleb survival as an adjunct therapy to glaucoma filtration surgery (GFS) in the rabbit model....

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Detalles Bibliográficos
Autores principales: Rodgers, Cooper D, Lukowski, Zachary L, Min, Jeff, Martorana, Gina M, Wilson, Mary-Kate, Schaefer, Jamie L, Levine, Monica A, Meyers, Craig A, Blake, C Richard, Schultz, Gregory S, Sherwood, Mark B
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Jaypee Brothers Medical Publishers 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6710929/
https://www.ncbi.nlm.nih.gov/pubmed/31496560
http://dx.doi.org/10.5005/jp-journals-10078-1246