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Interleukin (IL)-13 and IL-17A contribute to neo-osteogenesis in chronic rhinosinusitis by inducing RUNX2

BACKGROUND: There is increasing evidence supporting the impact of neoosteogenesis in the pathophysiology of chronic rhinosinusitis (CRS), especially in the recalcitrant group of patients. Runt-related transcription factor 2 (RUNX2), a member of the RUNX family, controls osteoblast differentiation an...

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Detalles Bibliográficos
Autores principales: Khalmuratova, Roza, Shin, Hyun-Woo, Kim, Dae Woo, Park, Jong-Wan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6710985/
https://www.ncbi.nlm.nih.gov/pubmed/31331833
http://dx.doi.org/10.1016/j.ebiom.2019.07.035