Early Histone Deacetylase Inhibition Mitigates Ischemia/Reperfusion Brain Injury by Reducing Microglia Activation and Modulating Their Phenotype

Histone deacetylase inhibitors (HDACi) are a promising therapeutic intervention for stroke. The involvement of the anti-inflammatory effects of HDACi in their neuroprotection has been reported, but the underlying mechanisms are still uncertain. Given the post-stroke inflammation is a time-dependent...

Descripción completa

Detalles Bibliográficos
Autores principales: Li, Shuyuan, Lu, Xiaoshuang, Shao, Qian, Chen, Zixin, Huang, Qiong, Jiao, Zinan, Huang, Xiaodi, Yue, Maosong, Peng, Jingwen, Zhou, Xin, Chao, Dachong, Zhao, Heng, Ji, Juling, Ji, Yuhua, Ji, Qiuhong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Neurology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6710990/
https://www.ncbi.nlm.nih.gov/pubmed/31481925
http://dx.doi.org/10.3389/fneur.2019.00893

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6710990/
https://www.ncbi.nlm.nih.gov/pubmed/31481925
http://dx.doi.org/10.3389/fneur.2019.00893

Ejemplares similares