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Effect of tissue permeability and drug diffusion anisotropy on convection-enhanced delivery
Although convection-enhanced delivery (CED) can successfully facilitate a bypass of the blood brain barrier, its treatment efficacy remains highly limited in clinic. This can be partially attributed to the brain anisotropic characteristics that lead to the difficulties in controlling the drug spatia...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Taylor & Francis
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6711026/ https://www.ncbi.nlm.nih.gov/pubmed/31357890 http://dx.doi.org/10.1080/10717544.2019.1639844 |