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Effect of tissue permeability and drug diffusion anisotropy on convection-enhanced delivery

Although convection-enhanced delivery (CED) can successfully facilitate a bypass of the blood brain barrier, its treatment efficacy remains highly limited in clinic. This can be partially attributed to the brain anisotropic characteristics that lead to the difficulties in controlling the drug spatia...

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Detalles Bibliográficos
Autores principales:	Zhan, Wenbo, Rodriguez y Baena, Ferdinando, Dini, Daniele
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Taylor & Francis 2019
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6711026/ https://www.ncbi.nlm.nih.gov/pubmed/31357890 http://dx.doi.org/10.1080/10717544.2019.1639844

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