Discovery of new butyrylcholinesterase inhibitors via structure-based virtual screening

Butyrylcholinesterase (BChE) plays an important role in the progression of the Alzheimer’s disease. In this study, we used a structure-based virtual screening (VS) approach to discover new BChE inhibitors. A ligand database was filtered and docked to the BChE protein using Glide program. The outcome...

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Detalles Bibliográficos
Autores principales: Atatreh, Noor, Al Rawashdah, Sara, Al Neyadi, Shaikha S., Abuhamdah, Sawsan M., Ghattas, Mohammad A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2019
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6711031/
https://www.ncbi.nlm.nih.gov/pubmed/31347933
http://dx.doi.org/10.1080/14756366.2019.1644329

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6711031/
https://www.ncbi.nlm.nih.gov/pubmed/31347933
http://dx.doi.org/10.1080/14756366.2019.1644329

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