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Intra-host emergence of an enterovirus A71 variant with enhanced PSGL1 usage and neurovirulence
Enterovirus A71 (EV-A71) is one of the main causative agents of hand-foot-and-mouth disease and is occasionally associated with severe neurological complications. EV-A71 pathophysiology is poorly understood due to the lack of small animal models that robustly support viral replication in relevant or...
Autores principales: | , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Taylor & Francis
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6711088/ https://www.ncbi.nlm.nih.gov/pubmed/31339457 http://dx.doi.org/10.1080/22221751.2019.1644142 |