Transcriptome analyses suggest minimal effects of Shank3 dosage on directional gene expression changes in the mouse striatum

Both deletions and duplications of the SH3 and multiple ankyrin repeat domains 3 (SHANK3) gene, encoding excitatory postsynaptic scaffolds, are causally associated with various brain disorders, suggesting that proper Shank3 dosage is critical for normal brain development and function. In addition to...

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Detalles Bibliográficos
Autores principales: Lee, Yeunkum, Kang, Hyojin, Jin, Chunmei, Zhang, Yinhua, Kim, Yoonhee, Han, Kihoon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2019
Materias:
Neurobiology & Physiology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6711111/
https://www.ncbi.nlm.nih.gov/pubmed/31489248
http://dx.doi.org/10.1080/19768354.2019.1595142

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6711111/
https://www.ncbi.nlm.nih.gov/pubmed/31489248
http://dx.doi.org/10.1080/19768354.2019.1595142

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