Co-delivery of Bmi1 small interfering RNA with ursolic acid by folate receptor-targeted cationic liposomes enhances anti-tumor activity of ursolic acid in vitro and in vivo

Overexpression of Bmi1 gene is an important feature of cancer stem cell in various human tumors. Therefore, Bmi1 gene can be a potential target for small interfering RNA (siRNA) mediated cancer therapy. Ursolic acid (UA) as a natural product plays a pivotal role in anti-tumor field, although its per...

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Detalles Bibliográficos
Autores principales: Li, Weijie, Yan, Ruicong, Liu, Yong, He, Chuanchuan, Zhang, Xiaojuan, Lu, Yao, Khan, Muhammad Waseem, Xu, Chuanrui, Yang, Tan, Xiang, Guangya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6711155/
https://www.ncbi.nlm.nih.gov/pubmed/31366257
http://dx.doi.org/10.1080/10717544.2019.1645244

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6711155/
https://www.ncbi.nlm.nih.gov/pubmed/31366257
http://dx.doi.org/10.1080/10717544.2019.1645244

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