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Pregnancy level of estradiol attenuated virus-specific humoral immune response in H5N1-infected female mice despite inducing anti-inflammatory protection

Estradiol, a major female steroid produced during pregnancy, has been reported to protect ovariectomized animals against H1N1 influenza infections via its anti-inflammatory effects. However, it remains unclear why pregnant women with high gestational estradiol levels are highly susceptible to influe...

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Detalles Bibliográficos
Autores principales: Finch, Courtney L., Zhang, Anding, Kosikova, Martina, Kawano, Toshiaki, Pasetti, Marcela F., Ye, Zhiping, Ascher, Jill R., Xie, Hang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6711175/
https://www.ncbi.nlm.nih.gov/pubmed/31364945
http://dx.doi.org/10.1080/22221751.2019.1648184