Drp1 Promotes KRas-Driven Metabolic Changes to Drive Pancreatic Tumor Growth

Mitochondria undergo fission and fusion to maintain homeostasis, and tumors exhibit the dysregulation of mitochondrial dynamics. We recently demonstrated that ectopic HRas(G12V) promotes mitochondrial fragmentation and tumor growth through Erk phosphorylation of the mitochondrial fission GTPase Dyna...

Descripción completa

Detalles Bibliográficos
Autores principales: Nagdas, Sarbajeet, Kashatus, Jennifer A., Nascimento, Aldo, Hussain, Syed S., Trainor, Riley E., Pollock, Sarah R., Adair, Sara J., Michaels, Alex D., Sesaki, Hiromi, Stelow, Edward B., Bauer, Todd W., Kashatus, David F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6711191/
https://www.ncbi.nlm.nih.gov/pubmed/31412251
http://dx.doi.org/10.1016/j.celrep.2019.07.031

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6711191/
https://www.ncbi.nlm.nih.gov/pubmed/31412251
http://dx.doi.org/10.1016/j.celrep.2019.07.031

Ejemplares similares