Cargando…

Context-Dependent Role for T-bet in T Follicular Helper Differentiation and Germinal Center Function following Viral Infection

Following infection, inflammatory cues upregulate core transcriptional programs to establish pathogen-specific protection. In viral infections, T follicular helper (TFH) cells express the prototypical T helper 1 transcription factor T-bet. Several studies have demonstrated essential but conflicting...

Descripción completa

Detalles Bibliográficos
Autores principales: Sheikh, Amania A., Cooper, Lucy, Feng, Meiqi, Souza-Fonseca-Guimaraes, Fernando, Lafouresse, Fanny, Duckworth, Brigette C., Huntington, Nicholas D., Moon, James J., Pellegrini, Marc, Nutt, Stephen L., Belz, Gabrielle T., Good-Jacobson, Kim L., Groom, Joanna R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6711398/
https://www.ncbi.nlm.nih.gov/pubmed/31412245
http://dx.doi.org/10.1016/j.celrep.2019.07.034