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Chemotherapy‐induced cachexia dysregulates hypothalamic and systemic lipoamines and is attenuated by cannabigerol

BACKGROUND: Muscle wasting, anorexia, and metabolic dysregulation are common side‐effects of cytotoxic chemotherapy, having a dose‐limiting effect on treatment efficacy, and compromising quality of life and mortality. Extracts of Cannabis sativa, and analogues of the major phytocannabinoid Δ9‐tetrah...

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Detalles Bibliográficos
Autores principales: Brierley, Daniel I., Harman, Joe R., Giallourou, Natasha, Leishman, Emma, Roashan, Anna Emily, Mellows, Ben A.D., Bradshaw, Heather B., Swann, Jonathan R., Patel, Ketan, Whalley, Benjamin J., Williams, Claire M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6711413/
https://www.ncbi.nlm.nih.gov/pubmed/31035309
http://dx.doi.org/10.1002/jcsm.12426