Cargando…

The role of SIRT1 in skeletal muscle function and repair of older mice

BACKGROUND: Sirtuin 1 (SIRT1) is a NAD+ sensitive deacetylase that has been linked to longevity and has been suggested to confer beneficial effects that counter aging‐associated deterioration. Muscle repair is dependent upon satellite cell function, which is reported to be reduced with aging; howeve...

Descripción completa

Detalles Bibliográficos
Autores principales: Myers, Matthew J., Shepherd, Danielle L., Durr, Andrya J., Stanton, David S., Mohamed, Junaith S., Hollander, John M., Alway, Stephen E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6711423/
https://www.ncbi.nlm.nih.gov/pubmed/31197980
http://dx.doi.org/10.1002/jcsm.12437