Histaminergic transmission slows progression of amyotrophic lateral sclerosis

BACKGROUND: Histamine is an immune modulator, neuroprotective, and remyelinating agent, beneficially acting on skeletal muscles and promoting anti‐inflammatory features in amyotrophic lateral sclerosis (ALS) microglia. Drugs potentiating the endogenous release of histamine are in trial for neurologi...

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Detalles Bibliográficos
Autores principales: Apolloni, Savina, Amadio, Susanna, Fabbrizio, Paola, Morello, Giovanna, Spampinato, Antonio Gianmaria, Latagliata, Emanuele Claudio, Salvatori, Illari, Proietti, Daisy, Ferri, Alberto, Madaro, Luca, Puglisi‐Allegra, Stefano, Cavallaro, Sebastiano, Volonté, Cinzia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6711424/
https://www.ncbi.nlm.nih.gov/pubmed/31020811
http://dx.doi.org/10.1002/jcsm.12422