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Degenerate intervertebral disc‐like pH induces a catabolic mechanoresponse in human nucleus pulposus cells

Mechanical stimulation is known to influence intervertebral disc (IVD) cell behavior and function, but the effect on disc cells is routinely considered in isolation from other microenvironmental factors. Acidic pH has been shown to be a prominent and detrimental microenvironmental factor present in...

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Detalles Bibliográficos
Autores principales: Hodson, Nathan W., Patel, Sonal, Richardson, Stephen M., Hoyland, Judith A., Gilbert, Hamish T. J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Inc. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6711490/
https://www.ncbi.nlm.nih.gov/pubmed/31463436
http://dx.doi.org/10.1002/jsp2.1004