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Recombination and mutational robustness in neutral fitness landscapes

Mutational robustness quantifies the effect of random mutations on fitness. When mutational robustness is high, most mutations do not change fitness or have only a minor effect on it. From the point of view of fitness landscapes, robust genotypes form neutral networks of almost equal fitness. Using...

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Detalles Bibliográficos
Autores principales: Klug, Alexander, Park, Su-Chan, Krug, Joachim
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6711544/
https://www.ncbi.nlm.nih.gov/pubmed/31415555
http://dx.doi.org/10.1371/journal.pcbi.1006884