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Scalable, semi-automated fluorescence reduction neutralization assay for qualitative assessment of Ebola virus-neutralizing antibodies in human clinical samples

Antibody titers against a viral pathogen are typically measured using an antigen binding assay, such as an enzyme-linked immunosorbent assay (ELISA), which only measures the ability of antibodies to identify a viral antigen of interest. Neutralization assays measure the presence of virus-neutralizin...

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Detalles Bibliográficos
Autores principales: Postnikova, Elena N., Pettitt, James, Van Ryn, Collin J., Holbrook, Michael R., Bollinger, Laura, Yú, Shuǐqìng, Caì, Yíngyún, Liang, Janie, Sneller, Michael C., Jahrling, Peter B., Hensley, Lisa E., Kuhn, Jens H., Fallah, Mosoka P., Bennett, Richard S., Reilly, Cavan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6711594/
https://www.ncbi.nlm.nih.gov/pubmed/31454374
http://dx.doi.org/10.1371/journal.pone.0221407