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The role of structural pleiotropy and regulatory evolution in the retention of heteromers of paralogs

Gene duplication is a driver of the evolution of new functions. The duplication of genes encoding homomeric proteins leads to the formation of homomers and heteromers of paralogs, creating new complexes after a single duplication event. The loss of these heteromers may be required for the two paralo...

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Detalles Bibliográficos
Autores principales: Marchant, Axelle, Cisneros, Angel F, Dubé, Alexandre K, Gagnon-Arsenault, Isabelle, Ascencio, Diana, Jain, Honey, Aubé, Simon, Eberlein, Chris, Evans-Yamamoto, Daniel, Yachie, Nozomu, Landry, Christian R
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6711710/
https://www.ncbi.nlm.nih.gov/pubmed/31454312
http://dx.doi.org/10.7554/eLife.46754