Antifibrotic effect of methylated quercetin derivatives on TGFβ-induced hepatic stellate cells

Quercetin (QCT) and isorhamnetin (ISO), natural flavonoids, were both shown to possess antifibrotic activity in in vivo and in vitro models of hepatic fibrosis. Although ISO is a direct metabolite of QCT differing by a methyl group, it has been reported to be absorbed more adequately and eliminated...

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Detalles Bibliográficos
Autores principales: Ganbold, Munkhzul, Shimamoto, Yasuhiro, Ferdousi, Farhana, Tominaga, Kenichi, Isoda, Hiroko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6711851/
https://www.ncbi.nlm.nih.gov/pubmed/31467991
http://dx.doi.org/10.1016/j.bbrep.2019.100678

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6711851/
https://www.ncbi.nlm.nih.gov/pubmed/31467991
http://dx.doi.org/10.1016/j.bbrep.2019.100678

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