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The primitive growth factor NME7(AB) induces mitochondrially active naïve-like pluripotent stem cells

Naïve pluripotent stem cells (PSCs) display a distinctive phenotype when compared to their “primed” counterparts, including, but not limited to, increased potency to differentiate and more robust mitochondrial respiration. The cultivation and maintenance of naïve PSCs have been notoriously challengi...

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Detalles Bibliográficos
Autores principales: O'Reilly, Carla, Qi, Qian, Peters, Jennifer L., Cheng, Yong, Yoon, Sang-Oh, Han, Min-Joon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6711853/
https://www.ncbi.nlm.nih.gov/pubmed/31467990
http://dx.doi.org/10.1016/j.bbrep.2019.100656