Mitochondrion-processed TERC regulates senescence without affecting telomerase activities

Mitochondrial dysfunctions play major roles in ageing. How mitochondrial stresses invoke downstream responses and how specificity of the signaling is achieved, however, remains unclear. We have previously discovered that the RNA component of Telomerase TERC is imported into mitochondria, processed t...

Descripción completa

Detalles Bibliográficos
Autores principales: Zheng, Qian, Liu, Peipei, Gao, Ge, Yuan, Jiapei, Wang, Pengfeng, Huang, Jinliang, Xie, Leiming, Lu, Xinping, Di, Fan, Tong, Tanjun, Chen, Jun, Lu, Zhi, Guan, Jisong, Wang, Geng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Higher Education Press 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6711880/
https://www.ncbi.nlm.nih.gov/pubmed/30788732
http://dx.doi.org/10.1007/s13238-019-0612-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6711880/
https://www.ncbi.nlm.nih.gov/pubmed/30788732
http://dx.doi.org/10.1007/s13238-019-0612-5

Ejemplares similares