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Mitochondrial dysfunction in human primary alveolar type II cells in emphysema

BACKGROUND: Cigarette smoke is the main risk factor of pulmonary emphysema development, which is characterized by alveolar wall destruction. Mitochondria are important for alveolar type II (ATII) cell metabolism due to ATP generation. METHODS: We isolated ATII cells from control non-smoker and smoke...

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Detalles Bibliográficos
Autores principales: Kosmider, Beata, Lin, Chih-Ru, Karim, Loukmane, Tomar, Dhanendra, Vlasenko, Liudmila, Marchetti, Nathaniel, Bolla, Sudhir, Madesh, Muniswamy, Criner, Gerard J., Bahmed, Karim
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6711885/
https://www.ncbi.nlm.nih.gov/pubmed/31383554
http://dx.doi.org/10.1016/j.ebiom.2019.07.063