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Fractalkine Induces Hepcidin Expression of BV-2 Microglia and Causes Iron Accumulation in SH-SY5Y Cells

Fractalkine (CX3CL1) is a potent inflammatory mediator of the central nervous system, which is expressed by neurons and regulates microglial functions by binding to fractalkine receptor (CX3CR1). It has been demonstrated that neuroinflammation plays an important role in iron accumulation of the brai...

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Detalles Bibliográficos
Autores principales: Pandur, Edina, Tamási, Kitti, Pap, Ramóna, Varga, Edit, Miseta, Attila, Sipos, Katalin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6711953/
https://www.ncbi.nlm.nih.gov/pubmed/31172340
http://dx.doi.org/10.1007/s10571-019-00694-4