Albumin evokes Ca(2+)-induced cell oxidative stress and apoptosis through TRPM2 channel in renal collecting duct cells reduced by curcumin

In proteinuric nephropathies of chronic kidney disease, the epithelial cells of the nephron including the collecting duct are exposed to high concentrations of luminal albumin. Albumin is taken up from collecting duct cells by endocytosis causing excessive reactive oxygen species (ROS) production an...

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Detalles Bibliográficos
Autores principales: Nazıroğlu, Mustafa, Çiğ, Bilal, Yazğan, Yener, Schwaerzer, Gerburg K., Theilig, Franziska, Pecze, László
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6711968/
https://www.ncbi.nlm.nih.gov/pubmed/31455864
http://dx.doi.org/10.1038/s41598-019-48716-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6711968/
https://www.ncbi.nlm.nih.gov/pubmed/31455864
http://dx.doi.org/10.1038/s41598-019-48716-x

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